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Description

Glutathione is a naturally occurring antioxidant that is present or plays a role in almost every cell within the body

PLoS ONE 15 , e0228104 (2020)

GSK3B is known for its role as a negative regulator for transcription factors, microtubules, and Wnt signalling, as well as in the hormonal control of glucose homeostasis as well as neurological disorders 26,27 This crystal structure reveals that VAL 135 and ASP 133 are important, and interactions with these amino acids may enhance the inhibitors activity (Fig